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. 2023 Jun 6;14:1149665. doi: 10.3389/fphar.2023.1149665

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Copyright © 2023 Zhang, Zhu, Yuan, Cheng, Xu, Chen, Pan and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of PTRF and the proteins in the PI3K/Akt signaling pathway in NAFLD/RA rats. (A) Western blot analysis of the expression of the proteins PTRF, PI3K (p85), p-PI3K, Akt, and p-Akt in liver tissues. (B) Densitometric analysis of PTRF expression. GAPDH was used as the internal control. (C) Representative quantitative analyses of PI3K (p85), p-PI3K, Akt, and p-Akt levels. Data are reported as mean ± SD (n = 3). *p < 0.05 vs. control group, ^# p < 0.05 NAFLD + CIA/AAV-NC, ^& p < 0.05 NAFLD/AAV-NC.