Table 2. Spectra of mutations induced by oxidatively damaged nucleotides.
Mutations | Damaged nucleotides added | |||
---|---|---|---|---|
None | 0.04 µM 2-OH-dATP | 2 µM 2-OH-dATP | 2 µM 8-OH-dGTP | |
C→T | 6 | 1 | 7 | 2 |
G→T | 1 | 9 | 41 | 0 |
G→C | 3 | 2 | 0 | 1 |
A→C | 0 | 0 | 0 | 12 |
G deletion | 1 | 0 | 0 | 0 |
Total | 11 | 12 | 48 | 15 |