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. 2023 Jun 6;14:1202044. doi: 10.3389/fendo.2023.1202044

Table 1.

Demographic, clinical and IVF treatment characteristics.

Variables Naturally conceived Frozen embryo transfers
Modified natural cycle Programmed cycle P-value
(n=1334) (n=217) (n=635)
Maternal age (years) 28.9 (4.8) 31.1 (5.6) 30.2 (5.1) <0.001***
Paternal age (years) 30.2 (5.4) 32.2 (6.9) * 31.4 (6.0) * <0.001
Maternal BMI (kg/m2) 20.8 (3.1) 21.5 (3.9) * 21.8 (4.1) * <0.001
Parity (n (%)) <0.001***
• first 983 (73.7) 181 (83.4) 586 (92.3)
• high order 351 (26.3) 36 (16.6) 49 (7.7)
Duration of infertility (m) 33.0 (27.0) 34.0 (27.0) <0.001
Type of infertility 0.144
• primary infertility 112 (51.6) 364 (57.3)
• secondary infertility 105 (48.4) 271 (42.7)
Cause of infertility 0.103
• female 105 320
• male 28 83
• mixes 74 209
• unexplained 9 66
b-AMH (ng/mL) 3.6 (3.2) 4.9 (5.3) 0.859
Total antral follicle count 14 (8.75) 15 (8) 0.071
EMT (mm) 9.7 (2.6) 9.0 (2.0) 0.002
Embryo stage at transfer 0.863
• Cleavage stage 68 (31.3) 195 (30.7)
• blastocyst 149 (68.7) 440 (69.3)
No. of embryos transferred <0.001
• single 135 (62.2) 242 (38.1)
• double 79 (36.4) 383 (60.3)
• triple 3 (1.4) 10 (1.6)

BMI, body mass index.

AMH, anti-Müllerian hormone.

E2, serum estradiol.

EMT, endometrial thickness.

Skewed data were presented as median (with interquartile range).

Categorical data was expressed as the number of cases (as a percentage of the total).

P-value <0.05 was considered statistically significant.

*Significantly different from the naturally conceived group.

**Significantly different from the naturally conceived group and natural cycle group.

***Significant differences were found between any two groups.