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. 2023 Jun 6;14:1202044. doi: 10.3389/fendo.2023.1202044

Table 3.

Unadjusted and adjusted odd ratios of placental developmental abnormalities in different cycles of frozen embryo transfer.

Naturally conceived Frozen embryo transfers
Reference group Modified natural cycle Programmed cycle
Variables (n=1334) (n=217) (n=635)
unadjusted adjusted unadjusted adjusted
OR (95%CI) P-value OR (95%CI) P-value OR (95%CI) P-value OR (95%CI) P-value
Abnormal placental morphology 14.39 (4.39-47.14) <0.001 4.35 (4.14-6.84) 0.148 8.60 (2.86-25.81) <0.001 5.27 (2.00-16.44) 0.002
Abnormal placental thickness / 0.140 / 0.986 / / / /
Abnormal placental position 3.39 (1.34-8.59) 0.016 3.83 (3.03-7.21) 0.143 3.48 (1.73-6.99) <0.001 3.84 (1.82-8.52) <0.001
Abnormal placental attachment 2.84 (1.28-6.33) 0.016 2.53 (2.08-4.73) 0.318 8.80 (5.32-14.55) <0.001 8.67 (5.24-14.98) <0.001
Intraplacental hematoma 1.0 (0.99-1.00) 1.000 / 0.973 1.26 (0.30-5.30) 1.000 0.51 (0.07-2.44) 0.427
Abnormal placental development 4.19 (2.51-6.99) <0.001 1.16 (1.31-7.01) 0.879 6.80 (4.71-9.83) <0.001 5.36 (3.63-8.05) <0.001

Adjusted for: maternal age, parity.