Table 1. Search Strategy Used for Medline.

1	shift work schedule/ or work schedule tolerance/
2	((shift* or night*) adj3 work*).ti,ab,kw.
3	((night* or rotat* or late) adj3 shift*).ti,ab,kw.
4	1 or 2 or 3
5	exp Sleep Wake Disorders/
6	(sleep* adj3 (disorder? or disturb* or problem?)). ti,ab,kw.
7	sleeplessness.ti,ab,kw.
8	(insomnia? or dysomnia? or parasomnia?).ti,ab,kw.
9	5 or 6 or 7 or 8
10	4 and 9
11	limit 10 to ("systematic review" or systematic reviews as topic or "reviews (maximizes specificity)")
12	randomized controlled trial.pt.
13	controlled clinical trial.pt.
14	randomized.ab.
15	placebo.ab.
16	drug therapy.fs.
17	randomly.ab.
18	trial.ab.
19	groups.ab.
20	(crossover or cross over).ti,ab.
21	(quasi* adj2 random*).ti,ab.
22	12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21
23	exp animals/ not humans.sh.
24	22 not 23
25	10 and 24
26	11 or 25