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. 2023 Mar 22;56(6):e13401. doi: 10.1111/cpr.13401

FIGURE 5.

FIGURE 5

Effects of SASP and PBMCs on Caco‐2 cell biology. Panel A: Caco‐2 cells were incubated with 60D SASP and/or PBMCs as reported in methods. The histograms show the percentage of cycling, quiescent, stressed and senescent cells following this treatment. Panel B, C, D: Apoptosis, soft agar colony formation, and cell migration were evaluated on Caco‐2 cells treated as indicated in panel A. Panel E: representative plots of flow cytometry analysis carried on naïve PBMCs or on those incubated with SASP and Caco‐2 cells. For all the assays, the symbols **p < 0.01 and *p < 0.05 indicate statistical significance between the control and irradiated samples.