Table 1.

Original condensed protocol sampling guidelines with addition of pTDP-43 as applied to the hospital autopsy cohort

		Regions sampled	Immunohistochemical stain
Block 1	Thal phase	Right occipital cortex	Beta-amyloid
		Right basal ganglia
		Midbrain
		Cerebellum
Block 2	Braak stage	Right hippocampus	Phosphorylated tau
	LATE stage	Right temporal (scored 2×)	Phosphorylated TDP-43
		Right frontal
		Left occipital (scored 1×)
Block 3	CERAD score	Left hippocampus	Bielschowsky
		Left temporal (scored 2×)
		Left frontal (scored 1×)
		Right parietal
Block 4	Lewy body stage	Pons	Alpha-synuclein
		Amygdala
		Cingulate
		Left parietal
Block 5	Vascular brain injury	Right thalamus	None
		Left thalamus (scored 1×)
		Left basal ganglia
		Medulla