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. 2023 Jun 6;13:1172606. doi: 10.3389/fonc.2023.1172606

Table 1.

Description of the study population.

No WFs at diagnosis All IPMNs
No. of patients with progression (%) No. of patients with no progression (%) No. of patients with progression (%) No. of patients with no progression (%)
Branch-duct IPMN 78 (26) 204 (68) 91 (26) 223 (63)
Mixed-type IPMN 12 (4) 3 (1) 22 (6) 9 (3)
Main-duct IPMN 1 (0.34) 0 7 (2) 2 (0.6)
Age, median (IQR), years 68 (61.0–68.0) 66 (60.0–72.0) 67 (60.0–73.0) 67 (60.0–73.0)
Follow-up time, median (IQR), months 67 (37.0–104.0) 59.99 (32.3–90.03) 60 (31.5–91.17) 61.7 (31.6–92.05)
Sex
Male 43 (14) 73 (24) 60 (17) 89 (25)
Female 48 (16) 134 (45) 60 (17) 145 (41)
BMI
<18 7 (2) 11 (4) 7 (2) 12 (3)
18–25.9 45 (15) 126 (42) 59 (16) 138 (39)
26–29.9 26 (9) 53 (18) 34 (10) 62 (18)
≥30 106 (36) 11 (4) 13 (4) 17 (5)
Not available 3 (1) 7 (2) 7 (1) 5 (1)
Smoking
No (never) 61 (20) 135 (45) 76 (22) 149 (42)
Yes 30 (10) 72 (24) 44 (12) 85 (24)
Alcohol consumption
No (never) 53 (18) 118 (40) 67 (19) 134 (38)
Yes 38 (13) 89 (30) 53 (15) 100 (28)
Type 2 diabetes
No 78 (26) 187 (63) 103 (29) 210 (60)
Yes 13 (4) 20 (7) 17 (5) 24 (7)
Cyst size at diagnosis (mm)
<15 32 (11) 125 (42) 40 (11) 133 (38)
15.1–29.9 59 (20) 82 (28) 59 (17) 84 (24)
≥30 21 (6) 17 (5)

Age and progression time are expressed in years and months, respectively. Progression means patients without WFs or HRSs and patients with WFs at diagnosis who developed the first or an additional WF or HRS during the follow-up. No progression means the no-development of new WFs or HRSs during the follow-up.

BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); IQR, interquartile range; WFs, worrisome features; HRSs, high-risk stigmata; IPMN, intraductal papillary mucinous neoplasm.