Table 1.
Demographics and baseline characteristics
| Total n = 100 | GE n = 50 | GL n = 50 | p-value | |
|---|---|---|---|---|
| Age (Years) | 44 ± 11 | 41 ± 10 | 47 ± 10 | 0.004 |
| Male/Female | 63/37 | 29/21 | 34/16 | 0.300 |
| SOFA | 6 ± 4 | 5.93 ± 4.65 | 6.10 ± 3.56 | 0.807 |
| BMI (kg/m2) | 34.4 ± 6.3 | 35.4 ± 6.0 | 33.4 ± 6.5 | 0.121 |
| Hypertension, n (%) | 38 (38) | 21 (42) | 17 (34) | 0.410 |
| Diabetes, n (%) | 25 (25) | 10 (20) | 15 (30) | 0.248 |
| Other comorbidities, n (%) | 19 (19) | 24 (48) | 14 (28) | 0.039 |
| Lactate (mmol/L) | 2.2 [1.2–2.5] | 2.5 [0.9–3.1] | 2.0 [1.2–2.38] | 0.401 |
| PaO2/FiO2 (mmHg) | 73 [62–154] | 73 [59–128] | 81 [62–170] | 0.595 |
| PaCO2 (mmHg) | 52 [46–62] | 48 [41–54] | 56 [46–67] | 0.115 |
| PEEP (cm H2O) | 14 [10–15] | 16 [14–16] | 12 [10–14] | 0.027 |
| Ppeak (cm H2O) | 29 [25–35] | 37 [29–39] | 28 [25–31] | 0.011 |
| Driving pressure (cm H2O) | 14 [10–18] | 23 [21–25] | 12 [9–18] | 0.030 |
| D-Dimer (mcg/mL) | 2.11 [1.29–5.57] (n = 26) | 2.01 [1.51–3.97] (n = 12) | 4.51 [1.25–78] (n = 14) | 0.368 |
| CRP (mg/dL) | 11.60 [4.25–23.40] (n = 32) | 13.1 [9.5–20.3] (n = 9) | 8.7 [3.2–26.9] (n = 23) | 0.4892 |
| Ferritin (ng/mL) | 1132 [618–2592] (n = 26) | 1339 [631–1927] (n = 10) | 1061 [405–2768] (n = 16) | 0.712 |
| MV before ECMO (h) | 19.5 [7–43] | 16 [5–25] | 39 [12–87] | 0.001 |
| MV before HA (h) | 25 [13–79] | 16 [5–29] | 79 [21–146] | < 0.001 |
| ECMO before HA (h) | 0 [0–5] | 0 [0–1] | 1 [0–78] | < 0.001 |
| ICU admission to ECMO (h) | 58 [35–138] | 37 [17–41] | 138 [87–231] | < 0.001 |
| ICU admission to HA (h) | 86 [38–186] | 38 [19–42] | 186 [119–304] | < 0.001 |
Data are presented as n (%), median [interquartile range] or mean ± standard deviation as appropriate