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. 2023 Jun 19;21:398. doi: 10.1186/s12967-023-04226-z

Table 2.

Results of serum total carnitine levels and free carnitine levels between the ME/CFS/SEID patient group and the healthy control group

Total carnitine levels, μmol/L (SD) Free carnitine levels, μmol/L (SD)
Study ME/CFS/SEID patient group Healthy control group P-valuea ME/CFS/SEID patient group Healthy control group P-valuea
Kuratsune H, et al. [12] No data No data 51.8 (9.5) 56.2 (9.7) NS
Kuratsune H, et al. [13] No data No data M 53.5 (8.5), F 46.8 (8.2) No data NS
Plioplys AV, et al. [14] M 49.9 (9.1), F 41.2 (9.5) M 59.3 (11.9), F 51.5 (11.6) p < 0.05 M 40.6 (8.9), F 32.1 (6.9) M 46.8 (10.0), F 40.1 (9.5) p < 0.05
Kuratsune H, et al. [15]b No data No data 34.8 (7.8) 38.5 (8.1) p < 0.05
Kuratsune H, et al. [15]c No data No data No data M 56.1 (10.7), F 43.6 (10.0)
Soetekouw PM, et al. [16] 46.9 (7.6) 48.9 (8.2) NS 35.4 (7.6) 36.8 (6.5) NS
Jones MG, et al. [17] 40.5 (8.7) 43.1 (9.8) NS 33.2 (7.9) 36.6 (9.5) NS
Reuter SE, et al. [18] 58.8 (13.6) 59.5 (12.9) NS 45.0 (11.3) 45.2 (9.79) NS

aIn each study, those for which a p-value was not calculated are shaded

bThe data in Swedish [15]

cThe data in Japanese [15]

ME myalgic encephalomyelitis, CFS chronic fatigue syndrome, SEID systemic exertion intolerance disease, SD standard deviation, M male, F female, NS not significant