Table 2.

Risk factors assessed in the included studies.

S. No.	Study (Year)	Arm	No. of pts	BMI (kg/m2)	Obesity	Hyper- Cholesterolemia	HT	DM	Smoking	Family History of CAD	Race (Caucasian)	Alcohol	Coffee/ Caffeine	OC	Parity	Marital Status	Post-menopause
1	Beckowski et al. (2018)	Case	1941	26.7 ± 5.3	433	700	966	203	944	339	N/A	N/A	N/A	N/A	N/A	N/A	N/A
		Control	1170	25.4 ± 4.8	182	141	189	21	457	433
2	Friedlander et al. (2001)	Case	107	29.3 ± 7.4	N/A	43	34	17	74	N/A	91	N/A	4.8 ± 5.4 cups/d	N/A	N/A	70	N/A N/A
		Control	526	24.8 ± 5.4		77	50	14	110	N/A	461		2.1 ± 3.0 cups/d			386
3	La Vecchia et al. (1987)	Case	52	<25: 36, >25: 16	16	5	14	5	40	26	N/A	Drinks/d <3: 19, ≥3: 10	Cups/d <4: 30, ≥4: 18	Current: 3, Past: 15	1-2: 33, ≥3: 8	36	7
		Control	91	<25: 70, >25: 21	21	3	5	2	39	42		Drinks/d <3: 46, ≥3: 6	Cups/d <4: 58, ≥4: 23	Current: 6, Past: 12	1-2: 37, ≥3: 24	61	7
4	Lewis et al. (1997)	Case	182	≤20: 17, 21-25: 64, 26-30: 51, >30: 42	42	20	42	14	146	39	N/A	35	N/A	Current: 57, First: 8	167	N/A	N/A
		Control	635	≤20: 97, 21-25: 329, 26-30: 131, >30: 75	75	14	50	12	233	40		152		Current: 156, First: 16	526
5	Liu et al. (2020)	Case	415	<24: 150, 24-26: 141, 27-29: 73, 30-39: 49, ≥40: 2	51	35	207	97	27	62	N/A	N/A	N/A	15	N/A	N/A	18
		Control	415	<24: 346, 24-26: 36, 27-29: 22, 30-39: 10, ≥40: 1	11	7	46	17	12	9				2			4
6	Oliveira et al. (2007)	Case	42	27.8 ± 5.7	N/A	13	16	4	28	12	Portuguese Caucasian	9.4 ± 15.3 g/d	96.6 ± 71.2 mg/d	N/A	N/A	N/A	N/A
		Control	486	24.9 ± 4.8		81	42	3	241	66		5.0 ± 9.3 g/d	80 ± 54.5 mg/d
7	Tanis et al. (2003)	Case	217	25.5 ± 5.0	64	23	55	11	180	141	206	N/A	N/A	85	N/A	N/A	N/A
		Control	763	23.4 ± 3.7	90	22	47	10	318	262	719			276

Abbreviations: BMI, body mass index; CAD, coronary artery disease; DM, diabetes mellitus; HT, hypertension; N/A, not available; OC, oral contraceptive; d, day; pts, patients.