TABLE 1.
Key features of the automated RPR tests
| Parameters |
Automated RPR |
||
|---|---|---|---|
| BioPlex RPR |
AIX 1000 |
ASI evolution |
|
| Turnaround (tests/hour)a | 200 | 192 | 190 |
| Specimen vialb | |||
| Type | Polystyrene / polypropylene | Polystyrene / polypropylene | Polystyrene / polypropylene |
| Dimension (mm) | 12 × 75 | 16 × 100 | 12 × 75 |
| Specimen volb | |||
| Qualitative / Screening (μL) | 240c | 305d | 300f |
| Quantitative low titer (μL) | 285c | 394d | 290f |
| Quantitative high titer (μL) | 405c | 220e | 140f |
| Titer rangea | |||
| Low titer | 1:4 to 1:64g | 1:1 to 1:16 | 1:1 to 1:64 |
| High titer | 1:128 to 1:2,048 | 1:16 to 1:256 | 1:128 to 1:2,048 |
a
Derived from product instructions for use. Refer to respective manufacturer’s instructions for more information.
b
Reported based on participating public health laboratories’ inputs.
c
Includes 230 μL of dead volume for BioPlex Syphilis Total & RPR.
d
Includes 300 μL of dead volume for qualitative/screening and quantitative low titer for AIX 1000.
e
Includes 200 μL of dead volume for quantitative high titer specimen for AIX 1000.
f
Includes 190 μL of dead volume for ASI Evolution.
g
A reactive specimen with titer less than 1:4 is reported as <1:4, and for greater than 1:64 as >1:64, requiring further testing following instructions from the manufacturer’s package insert.