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. 2023 Apr 14;72(7):986–998. doi: 10.2337/db22-1014

Figure 1.

Figure 1

IR expression and insulin/IGF-1 signaling in the gingiva of WT and SMIRKO mice. A: A schema of breeding between WT and SMIRKO mice. B: IRβ and IGF-1Rβ expression levels in the gingiva of WT and SMIRKO mice (N = 6). C–F: Insulin-induced signal transduction in the gingiva of WT and SMIRKO mice (N = 6). G–J: IGF-1–stimulated signal transduction in the gingiva of WT and SMIRKO mice (N = 6). *P < 0.05, **P < 0.01, ***P < 0.001. #P < 0.05, ###P < 0.001 versus WT 0 nmol/L. $P < 0.05, $$P < 0.01, $$$P < 0.001 versus SMIRKO 0 nmol/L. Blue circle, WT; orange square, SMIRKO.