Table 3.
Bivariate and Multivariate Analysis of Drug-Resistance Profiles by TB-HIV Co-Infection Status (N = 168)
| Drug-Resistance Profile | Categories | TB/HIV Co-Infection Status, N (%) | |||||
|---|---|---|---|---|---|---|---|
| TB with HIV, N (%) | TB Without HIV, N (%) | cOR (95% C.I) | P-value | aOR (95% C.I) | P-value | ||
| STR-related resistance¥ | Yes | 10 (6) | 14 (8.3) | 0.308 (0.123–0.771) | 0.012 | 0.298 (0.113–0.787) | 0.015⁎ |
| No | 26 (15.5) | 118 (70.2) | 1 (reference) | 1 (reference) | |||
| INH-related resistance¥ | Yes | 6 (3.6) | 11 (6.6) | 0.455 (0.156–1.328) | 0.149 | 0.570 (0.178–1.820) | 0.342 |
| No | 30 (17.9) | 121 (70.1) | 1 (reference) | 1 (reference) | |||
| EMB-related resistance¥ | Yes | 1 (0.6) | 5 (3) | 1.378 (0.156–12.18) | 0.773 | - | - |
| No | 35 (20.8) | 127 (75.6) | 1 (reference) | ||||
| MDR-TB | Yes | 5 (3) | 7 (4.2) | 0.347 (0.103–1.168) | 0.087 | 0.252 (0.73–0.875) | 0.030⁎ |
| No | 31 (18.5) | 125 (74.4) | 1 (reference) | 1 (reference) | |||
Notes: ¥Any drug resistance related to STR, INH, or EMB, excluding MDR-TB. ⁎Statistically significant.
Abbreviations: aOR, adjusted odds ratio; cOR, crudes odds ratio; CI, confidence interval; EMB, Ethambutol; HIV, Human Immune Virus; INH, isoniazid; MDR-TB, multidrug-resistant tuberculosis; RIF, Rifampicin; STR, Streptomycin.