Table 3.
Comparison of echocardiography parameters between PD patients and the control group.
| PD group baseline (32 patients) |
PD group follow-up (32 patients) |
Variant rate of PD group (%) | P* | Control group baseline (32 patients) |
Control group follow-up (32 patients) |
Variant rate of control group (%) | P** | P*** | |
|---|---|---|---|---|---|---|---|---|---|
| LVEF, % | 61.0 (58.3–66.8) |
62.5 (59.3–69.8) |
4.4 (−2.8 − 9.4) |
0.007 | 65.0 (59.0–69.0) |
61.0 (60.0–67.0) |
−4.8 (−10.0 − 5.8) |
0.141 | 0.004 |
| LVEDd, mm | 51.0 (47.5–56.8) |
50.0 (47.0–55.5) |
−-0.9 (−8.1 − 4.0) |
0.110 | 50.0 (45.0-53.0) |
49.0 (44.0-52.0) |
−2.0 (−11.1 − 2.0) |
0.390 | 0.630 |
| LAd, mm | 45.0 (43.3–49.8) |
44.0 (40.0–48.00) |
−4.1 (−9.0 − 4.4) |
0.095 | 41.0 (38.0–46.0) |
41.0 (37.0–44.0) |
−4.4 (−12.2 − 7.7) |
0.089 | 0.837 |
| RVDd, mm | 37.5 (31.8–39.3) |
34.0 (30.8–40.3) |
−2.4 (−8.2 − 5.4) |
0.321 | 35.0 (31.8–38.3) |
33.0 (30.0–38.0) |
−5.6 (−10.0 − 9.0) |
0.433 | 0.975 |
| RAd, mm | 38.5 (32.8-44.0) |
35.5 (32.8–42.0) |
−2.5 (−7.1 − 4.6) |
0.242 | 36.0 (32.0–40.0) |
36.0 (31.0–38.0) |
−7.5 (−12.5–12.5) |
0.455 | 0.693 |
| IVSd, mm | 11.9 (10.1–13.9) |
11.4 (10.9–13.0) |
0 (−5.3 − 5.0) |
0.716 | 11.0 (10.0–12.0) |
11.0 (10.0–12.0) |
−3.0 (−9.1 − 9.1) |
0.114 | 0.258 |
Note: Baseline and follow-up data of LVEF, LVEDd, LAd and IVSd were available in 32 patients of the SV group and 31 patients of the control group. Baseline and follow-up data of RVDd and RAd were available in 18 patients of the SV group and 18 patients of the control group. SV:sacubitril-valsartan; LVEF: left ventricular ejection fraction; LVEDd: left ventricular end-diastolic diameter; LAd: left atrium diameter; RVDd: right ventricular diastolic diameter; Rad: right atrium diameter; IVSd: interventricular septum diastolic thickness. Data were expressed as median (interquartile range). P* represented comparison between baseline and follow-up data in the PD group. P** represented comparison between baseline and follow-up data in the control group. P*** represented comparison between variant rate of PD group and of control group.