Table 3.
Risk factors for hospitalisation among confirmed mpox cases
|
Frequencies |
Unadjusted OR |
Adjusted OR |
||||
|---|---|---|---|---|---|---|
| Not admitted (n=50 525) | Hospitalised (n=3388) | OR (95% CI) | p value | OR (95% CI) | p value | |
| Age group | ||||||
| 15–44 years | 41 657 (93·7%) | 2794 (6·3%) | NA | NA | NA | NA |
| 0–4 years | 149 (88·0%) | 21 (12·0%) | 2·10 (1·29–3·25) | 0·0015 | 2·12 (1·32–3·40) | 0·0020 |
| 5–14 years | 214 (92·6%) | 17 (7·4%) | 1·18 (0·70–1·88) | 0·50 | 0·81 (0·44–1·51) | 0·51 |
| 45–64 years | 8163 (94·0%) | 523 (6·0%) | 0·96 (0·87–1·05) | 0·35 | 0·97 (0·88–1·08) | 0·60 |
| ≥65 years | 315 (91·6%) | 29 (8·4%) | 1·37 (0·92–1·97) | 0·10 | 1·54 (1·05–2·25) | 0·026 |
| Unknown | 27 (87·0%) | 4 (13·0%) | 2·21 (0·65–5·65) | 0·14 | 1·98 (0·76–5·16) | 0·16 |
| Sex | ||||||
| Male | 46 906 (93·9%) | 3053 (6·1%) | NA | NA | NA | NA |
| Female | 1816 (90·7%) | 187 (9·3%) | 1·58 (1·35–1·84) | <0·0001 | 1·61 (1·35–1·91) | <0·0001 |
| Unknown | 1803 (92·4%) | 148 (7·6%) | 1·26 (1·06–1·49) | 0·0080 | 1·35 (1·13–1·62) | 0·0013 |
| HIV and immunocompromised status | ||||||
| HIV- and not immunosuppressed | 8445 (94·9%) | 457 (5·1%) | NA | NA | NA | NA |
| HIV+ and not immunosuppressed | 1540 (94·9%) | 82 (5·1%) | 0·98 (0·77–1·25) | 0·90 | 0·91 (0·71–1·16) | 0·44 |
| HIV- and immunosuppressed | 73 (86·9%) | 11 (13·1%) | 2·78 (1·39–5·06) | 0·0017 | 3·47 (1·84–6·54) | 0·0001 |
| HIV+ and immunosuppressed | 4387 (93·9%) | 287 (6·1%) | 1·21 (1·04–1·41) | 0·014 | 2·00 (1·68–2·37) | <0·0001 |
| Unknown | 36 080 (93·4%) | 2551 (6·6%) | 1·31 (1·18–1·45) | <0·0001 | 1·16 (1·03–1·31) | 0·014 |
Data are n (%) unless otherwise stated. Table includes unadjusted ORs, and results of multivariable binomial regression, where country was included as a random effect (not shown). Multivariable model included age, sex, and HIV and immunocompromised status as a predictor variables. The denominators used for calculating the frequency percentages is the sum of the number of cases in the not admitted and hospitalised columns. Older age groups (aged ≥65 years), children (aged <5 years), and immunocompromised individuals, regardless of HIV status, were most at risk for hospitalisation. NA=not applicable. OR=odds ratio.