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. Author manuscript; available in PMC: 2023 Jun 20.
Published in final edited form as: Trends Biochem Sci. 2022 May 23;47(11):978–988. doi: 10.1016/j.tibs.2022.05.001

Table 1.

Validated mammalian viral suppressors of RNAi

VSR Virus Family Mechanism Refs
B2 Nodamura virus Nodaviridae (+RNA genome) dsRNA sequestration [11,12,21,22,24]
NS1 Influenza A virus Orthomyxoviridae (−RNA genome) dsRNA sequestration [13,22,43]
3A Enterovirus-A71 Picornaviridae (+RNA genome) dsRNA sequestration [14,35]
NS2A Dengue virus 2 Flaviviridae (+RNA genome) dsRNA sequestration [16]