Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The mechanism of MGF in inflammatory reactions and cell apoptosis
(A) MGF can downregulate the expressions of inflammatory factors, such as IL-1β, TNF-α, and MMP3, in chondrocytes and synoviocytes. (B) Excessive mechanical stress and OA induce cell apoptosis, which can be inhibited by exogenous MGF by regulating the expressions of Bcl-2, Bax, caspase-3, caspase-8 and CHOP.
