. 2023 Jun 10;12(6):1677–1693. doi: 10.1007/s40121-023-00821-1

Table 3.

Comparison of incidence and hazard ratio of acute abdomen between dengue and nondengue cohorts stratified by follow-up period

Acute abdomen	Dengue cohort		Non-dengue cohort		Adjusted HR^b (95% CI)^d	P value^e	Adjusted SHR^c (95% CI)^d	P value^e
Acute abdomen	No. of events	IR^a	No. of events	IR^a	Adjusted HR^b (95% CI)^d	P value^e	Adjusted SHR^c (95% CI)^d	P value^e
Acute cholecystitis
≤ 30 days	121	18.79	8	0.31	60.21 (29.11–124.54)	< 0.0001*	60.01 (28.24–127.53)	< 0.0001*
≤ 10 days	110	51.13	4	0.46	111.67 (40.80–305.65)	< 0.0001*	111.44 (39.76–312.31)	< 0.0001*
11–30 days	11	2.56	4	0.23	9.25 (2.79–30.65)	0.0003*	9.23 (2.57–33.18)	0.0007*
31–365 days	68	0.95	212	0.74	1.32 (0.99–1.74)	0.0579	1.32 (0.99–1.75)	0.0576
> 365 days	375	1.19	1437	1.14	1.01 (0.90–1.13)	0.9293	1.03 (0.91–1.16)	0.6488
Acute pancreatitis
≤ 30 days	34	5.27	8	0.31	17.13 (7.66–38.29)	< 0.0001*	17.02 (7.95–36.46)	< 0.0001*
≤ 10 days	^e	^e	^e	^e	45.65 (10.64–195.93)	< 0.0001*	45.51 (11.77–176.01)	< 0.0001*
11–30 days	^e	^e	^e	^e	5.54 (1.66–18.44)	0.0053	5.53 (1.54–19.90)	0.0088
31–365 days	33	0.46	119	0.41	1.15 (0.77–1.71)	0.4986	1.15 (0.78–1.71)	0.4885
> 365 days	183	0.58	666	0.53	1.11 (0.94–1.32)	0.2127	1.14 (0.96–1.35)	0.1374
Acute appendicitis
≤ 30 days	10	1.55	23	0.89	1.65 (0.78–3.49)	0.1952	1.64 (0.76–3.55)	0.2086
≤ 10 days	^e	^e	^e	^e	3.74 (1.39–10.09)	0.0091	3.74 (1.29–10.83)	0.0150
11–30 days	^e	^e	^e	^e	0.51 (0.11–2.25)	0.3720	0.51 (0.12–2.15)	0.3560
31–365 days	51	0.71	208	0.72	1.01 (0.74–1.38)	0.9591	1.01 (0.74–1.38)	0.9558
> 365 days	285	0.90	882	0.70	1.32 (1.15–1.51)	< 0.0001*	1.33 (1.12–1.52)	< 0.0001*

^aIR = incidence rate per 10,000 person-months

^bHazard ratio adjusted for age, sex, area of residence, urbanization level, monthly income level, and comorbidities

^cSubdistribution hazard ratio adjusted for age, sex, area of residence, urbanization level, monthly income level, and comorbidities

^d95% CIs were not adjusted for multiple comparisons and thus cannot be directly used for hypothesis testing or inference

^eThe cells left blank indicated that the numbers of events in some cells was too small and were therefore not allowed to be exported under the regulations of the Health and Welfare Data Science Center of Taiwan to prevent re-identification

^fPost hoc adjustment for multiple comparisons by the Bonferroni method required a significance level of P < 0.0013

*Achieved statistical significance after Bonferroni correction for multiple comparisons (P < 0.0013)