Ovid MEDLINE(R) and Epub Ahead of Print, In‐Process, In‐Data‐Review & Other Non‐Indexed Citations, Daily and Versions 1946 to July 29, 2022
#	Searches	Results
1	pentoxifylline/ [MeSH/EMTREE]	4320
2	(agapurin or artal or azupentat or azutrenat or bl 191 or bl191 or c‐vex or carpental or cental or ceretal or claudicat retard or "eht 0201" or eht0201 or elorgan or erytral or fixoten or flexital or harin or harine or hemovas or ikomio or ipentol or kentadin or oxopurin 400 sr or oxpentifylline or oxpentiphylline or oxypentifylline or penphylline or pentong or pentopak or pentox* or pentyllin or perencal or perental or peridane or pexal or pexol or platof or ralofect or ralofekt or relofekt or rentylin or tarontal or thrental or torental or torestal or trenfyl or trenlin or trental or trepal‐400 or vazofen).ti,ab,kw,kf.	7236
3	or/1‐2 [Pentoxifylline]	7879
4	exp Phosphodiesterase Inhibitors/	88829
5	(Phosphodiesteras* adj2 Inhibit*).ti,ab,kw,kf.	13372
6	or/4‐5 [Drug category]	93687
7	exp sepsis/	136863
8	exp enterocolitis/ [includes necrotising]	14504
9	(sepsis* or septic* or Pyemia* or Pyohemi* or Pyaemi* or ((blood* or bloodstream*) adj2 (infect* or poison*))).ti,ab,kw,kf.	197502
10	(enterocoliti* or colienteriti* or NEC).ti,ab,kw,kf.	22328
11	or/7‐10 [NEC or Sepsis]	285286
12	exp Infant, Newborn/ or Intensive Care, Neonatal/ or Intensive Care Units, Neonatal/ or Gestational Age/	707018
13	(babe or babes or baby* or babies or gestational age? or infant? or infantile or infancy or low birth weight or low birthweight or neonat* or neo‐nat* or newborn* or new born? or newly born or premature or pre‐mature or pre‐matures or prematures or prematurity or pre‐maturity or preterm or preterms or pre term? or preemie or preemies or premies or premie or VLBW or VLBWI or VLBW‐I or VLBWs or LBW or LBWI or LBWs or ELBW or ELBWI or ELBWs or NICU or NICUs).ti,ab,kw,kf.	1004443
14	or/12‐13 [Filter: Neonatal Population 04‐2022‐MEDLINE]	1313879
15	randomized controlled trial.pt.	574087
16	controlled clinical trial.pt.	94966
17	randomized.ti,ab.	619035
18	placebo.ti,ab.	236764
19	drug therapy.fs.	2516603
20	randomly.ti,ab.	389079
21	trial.ti,ab.	709192
22	groups.ti,ab.	2415024
23	or/15‐22 [Cochrane HSSS‐SM Filter; Box 6.4.a Cochrane Handbook]	5488787
24	(quasirandom* or quasi‐random* or randomi* or randomly).ti,ab,kw,kf.	1058014
25	(control* adj2 (group? or random* or trial? or study)).ti,ab,kw,kf.	1053768
26	or/24‐25 [Additional terms to increase sensitivity]	1636420
27	exp animals/ not humans/	5033285
28	(or/23,26) not 27 [RCT Filter: Medline]	5031488
29	meta‐analysis/ or "systematic review"/ or network meta‐analysis/ [/ finds same as.pt. syntax]	281523
30	((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab,kf,kw.	278904
31	((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab,kf,kw.	35286
32	(data synthes* or data extraction* or data abstraction*).ti,ab,kf,kw.	36171
33	(hand search* or handsearch*).ti,ab,kf,kw.	10608
34	(mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab,kf,kw.	32709
35	meta‐analysis as topic/ or network meta‐analysis/	25398
36	(meta analy* or metanaly* or meta regression* or metaregression*).ti,ab,kf,kw.	243644
37	(medline or cochrane or pubmed or medlars or embase or cinahl).ab.	297414
38	(cochrane or systematic review?).jw.	19418
39	or/29‐38 [SR filter‐Medline; based on CADTH https://searchfilters.cadth.ca]	562706
40	3 and 14 [Pentoxifylline AND Neontal Terms]	197
41	6 and 11 and 14 [Drug Cateory AND NEC/Sepsis AND Neonatal Terms]	118
42	or/40‐41 [Results before filters]	270
43	42 and 28 [RCT Results]	130
44	42 and 39 and 202*.yr. [Systematic reviews 2020 forward]	1
45	or/43‐44 [All Results]	130