Sareno 2013.
Methods | Randomised controlled trial where participants were randomised to receive either pentoxifylline at a dose of 6 mg/kg/h or placebo |
Participants | Preterm infants ≤ 1500 g with suspected infection admitted to the neonatal intensive care unit. Infants with major congenital malformations, congenital infections, and severe haemorrhage were excluded from the study. |
Interventions | Pentoxifylline at a dose of 6 mg/kg/h or placebo. Pentoxifylline was administered as a 6 mL infusion for 6 hours for 6 days. The control group received normal saline in the same manner as the pentoxifylline infusion. Infants, parents, and physicians (outcome assessors) were blinded to the treatment assignments. |
Outcomes | The primary outcome measured in the study was the occurrence of all‐cause mortality between groups. Secondary outcomes measured include mortality from sepsis, adverse drug reactions, and length of hospital stay. The primary outcome was analysed on an intention‐to‐treat basis. |
Notes | Published as an abstract. We contacted the author for more details, but as of yet have received no response. |