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. 2023 Jun 7;14:1065609. doi: 10.3389/fmicb.2023.1065609

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Copyright © 2023 Collett, Earnest, Carrera Montoya, Edeling, Yap, Wong, Christiansen, Roberts, Mumford, Lecouturier, Pavot, Marco, Loi, Simmons, Gulab, Mackenzie, Elbourne, Ramsland, Cameron, Hans, Godfrey and Torresi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NKT cell activation induced by self-adjuvanted HCV and SARS CoV-2 VLPs. Splenocytes (C57BL/6) were stimulated for 4 days in vitro. Numbers on FACS plots indicate the percentage of NKT cells amongst viable (7-AAD-), CD19- lymphocytes from (A) SARS CoV-2 or (C) HCV VLPs generated in the presence of the indicated dose of α-GalCer shown in comparison to α-GalCer alone or vehicle controls. Pooled data of NKT cells percentages following in vitro culture with (B) SARS CoV-2 or (D) HCV VLPs. Data sourced from three independent experiments.