Table 3.

Multifactor Logistics Regression Analysis of Influencing Factors of Necrotizing Enterocolitis and Feeding Intolerance

Outcome	Groups	Ratio	Predicted probabilities (95%CI)	OR (95% CI)	p
NEC	High HM	4/214 (1.9%)	1.0 − 1.2%
	Low HM	18/64 (28.1%)	22.7 − 29.1%	33.526 (7.183–156.475)	<0.001
	Formula	2/25 (8.0%)	7.3 − 11.8%	8.493 (1.107–65.187)	0.040
Feeding intolerance	High HM	44/214 20.6%)	17.7 − 19.6%
	Low HM	39/64 (60.9%)	51.7 − 57.3%	4.383 (2.243–8.564)	<0.001
	Formula	9/25 (36%)	27.4 − 29.9%	1.021 (0.347–3.006)	0.970

Multivariate logistic analysis was adjusted with gestational age, birth weight, 1-minute Apgar score, probiotics, fortifier and prolonged empirical antibiotics exposure (longer than 5 days). High HM, the proportion of HM more than 54%. Low HM, the proportion of HM less than 54%. The high HM group was the reference group.

CI, confidence interval; HM, human milk; NEC, necrotizing enterocolitis.