. Author manuscript; available in PMC: 2023 Jun 21.

Published in final edited form as: Ophthalmol Retina. 2022 Apr 9;6(9):771–785. doi: 10.1016/j.oret.2022.03.024

Table 6.

Visual Acuity Change (in Letters) over 4 Weeks by Change in Intraretinal Fluid Status between Adjacent 4-Week Visits

Visual acuity change over 4 wks by fluid variables
			Unadjusted		Adjusted ^*
	Intraretinal Fluid Status in Adjacent Visits (Previous Visit/Current Visit)	n	Mean Change (95% CI)	P^†	Mean Change (95% CI)	P^†
Change in intraretinal fluid status over 4 wks	Present/present	3808	0.04 (0.08)	< 0.001	0.03 (0.08)	< 0.001
	Not present/present	1537	−0.71 (0.17)		−0.66 (0.18)
	Present/not present	1564	0.56 (0.15)		0.52 (0.16)
	Not present/not present	2570	0.15 (0.07)		0.19 (0.08)

CI = confidence interval.

Adjusted by baseline predictors of visual acuity, including age, visual acuity, macular neovascularization area, macular neovascularization lesion type, study eye macular atrophy, total foveal thickness, retinal pigment epithelium elevation, drug, and subretinal fluid.

^†

All 4 fluid status variables were considered simultaneously in a model of visual acuity.