Table 1.

Summary of cluster content, delineated by cluster name, total retweets (RT), average retweets per cluster (Rc), and example tweets. Due to Twitter’s terms of service restrictions, tweets outlined in our table have been abridged to prevent identification.

Cluster name	RT	Rc	Tweets, n	Sample tweets
Cynicism	91,483	29.68	3082	“Just wait, 2 years from now we’ll have Omega Mpox -- Mpox isn’t airborne, so far as I know, there’s that ‘emergency’ -- So many other illnesses happen every day yet those don’t get sensationalized”
Exasperation	17,495	3.76	4649	“Twitter is loving the Mpox doom narrative, huh? -- Biden liked it so much now he’s leading with a Mpox opening act! -- Here we go again with another breaking emergency like we aren’t all tired”
COVID-19	20,939	7.37	2840	“Mpox time! Get that toilet paper back on your face! -- Never forget that the government and media played into COVID-19 for hysteria -- Joe Biden mentioned we need more money for another pandemic”
MSMa	132,987	60.61	2194	“So this is like the HIV epidemic of the 80s huh? -- I guess I have nothing to worry about, this is a gay people thing -- So are you saying Mpox is a homosexual thing?”
Case reports	65,741	36.24	1814	“First Mpox case identified in NY, patient is stable -- Mpox detected in at least seven states, spread likely -- Mpox spreads to US: How to stay informed.”
Vaccination	22,733	13.06	1740	“The good news is a safe and effective vaccine exists, get yours today. -- If you are at high risk for developing Mpox, get your vaccine here -- Vaccines are the best way to protect you and yours from Mpox spread”
WHOb	97,591	73.54	1327	“WHO now says Mpox is an international health emergency -- Need Mpox resources? Read the WHO official statement -- WHO declares highest alert for an outbreak”

^aMSM: men who have sex with men.

^bWHO: World Health Organization.