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. Author manuscript; available in PMC: 2023 Jun 21.
Published in final edited form as: Drug Metab Rev. 2022 Aug 5;54(3):246–281. doi: 10.1080/03602532.2022.2097254

Figure 13.

Figure 13.

Proposed bioactivation pathway of tandutinib. Figure adapted from Al-Shakliah et al. (2021). KCN: potassium cyanide. Predicted structures of four cyano adducts (TNDCN588, TNDCN546, TNDCN574, and TNDCN602) are shown.