Table 3. Comparison of IC50 Values of PCB52 and its Human-Relevant Metabolites as Assessed by MTT Assay in Sex Segregated Rat Primary Astrocytesa.
PCB mixture | IC50 males (μM) | IC50 females (μM) |
---|---|---|
PCB52 | 15.3 | 14.4 |
4-OH-PCB52 | 4.9 | 4.4 |
4-OH-PCB52 sulfate | 7.0 | 6.9 |
Data were obtained from at least three biological replicates.