Figure 2.

HIIT ameliorates STZ-induced learning and memory deficits and neuronal degeneration. (A) Representative tracking plots and results of rats in the training trials of the Barnes maze tests. The slope of line (b) and the mean speed (c) were analyzed. (B) Results of the probe test in the Barnes maze tests (n = 7-12). (C) Representative immunofluorescence images of NeuN (red) and Fluoro-Jade C staining (green). The scale bar represents 10 μm. Line-scan analysis was performed to analyze the colocalization. The Fluoro-Jade C-positive neurons and surviving neurons were analyzed. Data represent mean ± SEM, n = 12 slices from 6 animals. ^*P < 0.05 vs. Cont group, ^#P < 0.05 vs. STZ group. ns represents no significant difference.