Table 5.

Common Barriers to Participant Recruitment (N=16)

Barriers	%
Patient-Specific*
Lack of time to participate in clinical trials	63%
Lack of awareness of the trial	50%
Lack of willingness to be randomized	44%
Lack of understanding about clinical trials (in general)	44%
Lack of trust in clinical research/research staff	31%
Preference toward standard therapy	31%
Anxiety/Concern around the informed consent process	25%
Motivation for treatment is variable+	6%
Trial-Specific*
Restrictive/Extensive eligibility criteria	75%
Study protocol complexity (not including eligibility criteria)	69%
Competition from nearby clinical trials	44%
Loss of staff motivation in recruitment	38%
Lack of coordination at trial start-up	19%

* Respondents may have multiple answers; ⁺ Specified by respondent