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. 2023 May 31;24:141. doi: 10.1186/s12931-023-02435-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Risk of outcomes based on the 52-gene signature. Kaplan-Meier plots show the time from enrollment to the composite outcome of lung transplant or death (A) and the composite outcome of ≥ 10% absolute decline in FVC % predicted, lung transplant, or death (B) for the high-risk group and low-risk group. The associated tables show the unadjusted hazard ratio and the hazard ratio adjusted for CPI and antifibrotic treatment use for the high-risk group compared to the low-risk group. HR: hazard ratio; PH: proportional hazards; CPI: composite physiologic index