Table 2.

Summary of ongoing studies of RNSM

Identifier	Sample size	Randomization	Indication	Intervention	Postoperative outcomes	Oncologic outcomes	PRO	Country of origin
NCT04585074 (current study)	2000	No	Women with breast cancer High-risk women	RNSM + ENSM CNSM	Yes	Yes	Yes	South Korea
NCT04108117	300	No	Women with breast cancer High-risk women	RNSM CNSM	Yes	Yes	No	South Korea
NCT03440398	82	Yes	Women with breast cancer High-risk women	RNSM CNSM	Yes	Yes	Yes	Italy
NCT03892980	145	No	High-risk women	RNSM	Yes	No	No	United States
NCT04537312	20	No	Women with breast cancer High-risk women	RNSM	Yes	No	Yes	United States
NCT04457167	480	No	Women with breast cancer High-risk women	RNSM CNSM	Yes	No	No	France
NCT04151368	30	No	Women with breast cancer High-risk women	RNSM	Yes	Yes	Yes	Canada
NCT04037852	180	No	Women with breast cancer	RNSM CNSM or ENSM	Yes	Yes	Yes	Taiwan

CNSM conventional nipple-sparing mastectomy, ENSM endoscopic nipple-sparing mastectomy, PRO Patient-reported outcome, RNSM robot-assisted nipple-sparing mastectomy