TABLE 2.
MICE USED IN THIS STUDY
|
Genetic Background |
Genotype |
Experiments (Figure No.) |
|---|---|---|
| C57BL6/N (B6) | Wild type | ELISA assay (Figure 2A) |
| RPA assay (Figures 2B and 2C) | ||
| Flow cytometry (Figure 3) | ||
| Histology (Figures 4A and 4B) | ||
| Wet lung weight (Figure 4C) | ||
| Hydroxyproline (Figure 4D) | ||
| BALF (Figure 5) | ||
| B6 × 129 (B6129 F1 hybrid) | Wild type | Histology (Figures 4A and 4B) |
| Wet lung weight (Figure 4C) | ||
| Hydroxyproline (Figure 4D) | ||
| B6 × 129 | IL-18Rα−/− | Histology (Figures 4A and 4B) |
| Wet lung weight (Figure 4C) | ||
| Hydroxyproline (Figure 4D) | ||
| B6 | IL-18Rα−/− | BALF (Figure 5) |
| B6 × 129 | Caspase-1−/− | Histology (Figures 4A and 4B) |
| Wet lung weight (Figure 4C) | ||
| Hydroxyproline (Figure 4D) | ||
| B6 | Caspase-1−/− | BALF (Figure 5) |
| B6 | IL-18−/− | Histology (Figures 4A and 4B) |
| Wet lung weight (Figure 4C) | ||
| Hydroxyproline (Figure 4D) | ||
| BALF (Figure 5) |
Definition of abbreviations: BALF, bronchoalveolar lavage fluid; RPA, RNase protection assay.