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. 2023 Jun 21;2023(6):CD014788. doi: 10.1002/14651858.CD014788.pub2

Gregoriou 1997.

Methods Randomisation: by sequential numerical allocation to a randomisation list before commencing trial
Participants Number of women: 40 
Age: Mean age of group 1: 28.3 years and mean age of group 2: 29.1 years
Inclusion criteria: 
  • minimum of 4 endometriotic lesions

  • endometriotic symptoms and pelvic pain graded at least 3 (severe)

  • negative cervical smear


Exclusion criteria: 
  • smoking

  • medications that might affect bone metabolism

  • medical conditions that could affect bone metabolism


Setting: Greece
Timing: not stated
Interventions Group 1: leuprolide acetate depot 3.75 mg IM every 4 weeks
versus
Group 2: leuprolide acetate depot 3.75 mg every 4 weeks + 1.25 mg daily oral conjugated equine oestrogens on days 1 to 25 and 5 mg oral medroxyprogesterone acetate on days 16‐25
Outcomes
  • Bone mineral density

Notes Intention‐to‐treat analysis: not stated
Sample size calculation: not stated 
Funding: not stated
This abstract did not contain enough information to make a proper decision about in‐/exclusion.