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. 2023 Jun 7;29:1611038. doi: 10.3389/pore.2023.1611038

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Copyright © 2023 Shen, Chen, Huang, Shyu, Seftor, Seftor, Hendrix, Chien and Chu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram showing the anti-tumor mechanisms of CVM-1118 via targeting TRAP1. Molecular mechanisms in tumor cells to show how TRAP1 mediates anti-apoptosis and promotes VM formation (A) and the effects of CVM-1118 treatment (B).