TABLE 3.

Kinetic and affinity constants (ka, kd, and K_D) to CVM-1125 determined by SPR.

No.	Protein	Association (ka) M−1s−1	Dissociation (kd) s−1	KD (kd/ka) M
1	TRAP1	3.02 × 104	2.2 × 10−3	6.68 × 10−8
2	ATP6IP2	1.22 × 105	2.1 × 10−2	1.73 × 10−7
3	CD18	14.4	1.08 × 10−5	7.48 × 10−7
4	Nucleolin	1.35 × 104	1.22 × 10−2	9.06 × 10−7
5	Catenin α2	No dose dependent interaction
6	Integrin β4	No dose dependent interaction
7	CEACAM5	No interaction
8	TGFβ1/1	No dose dependent interaction
9	GADD45GIP1	No interaction
10	Catenin β-1	No interaction
11	TGFβig-h3	No interaction