Supplemental Figure S6.

Box plots and beeswarm scatterplots of relative protein expression between two markers, predictive of distant metastasis, stratified by mismatch repair (MMR) status: CD8/programmed death ligand 1 (PD-L1) inside the tumor (Intra; A); CD4/PD-L1 inside the tumor (B); CD11c/granzyme B (GZMB) at the interface (Inter; C); and CD11c/CD34 away from tumor (Away; D). Marker expression plotted in beeswarm plots was filtered on the basis of detection of outliers using a modified Tukey outlier test—after this initial filtering, only points between the 10% and 90% quantiles for each stratum were included. Intra, Inter, and Away are described in Data Acquisition and Preprocessing. dMMR, MMR deficient; pMMR, MMR proficient.