Skip to main content
. 2023 Jun;193(6):778–795. doi: 10.1016/j.ajpath.2023.02.020

Figure 4.

Figure 4

Relative protein expression between markers predictive of nodal metastasis, stratified by mismatch repair (MMR) status: CD66b/CD8 inside the tumor (Intra; A); forkhead box P3 (FOXP3)/programmed death ligand 1 (PD-L1) inside the tumor (B); CD8/cytotoxic T-lymphocyte–associated antigen 4 (CTLA4) at the interface (Inter; C); and CD8/CD56 at the interface (D). Marker expression plotted in beeswarm plots was filtered on the basis of the detection of outliers using a modified Tukey outlier test—after this initial filtering, only points between the 10% and 90% quantiles for each stratum were included. Intra and Inter are described in Data Acquisition and Preprocessing. dMMR, MMR deficient; pMMR, MMR proficient.