Table 2.
Total n = 99 |
Aortic regurgitation | Aortic stenosis | P value | |
---|---|---|---|---|
n = 32 (32%) | n = 67 (68%) | |||
CMR to surgery (days) | 50 (33–70) | 55 (36–86) | 49 (28–67) | 0.251 |
Indexed LA (mm/m2) | 43 (38–52) | 45 (40–57) | 42 (36–50) | 0.107 |
Indexed LV end-diastolic volume (mL/m2) | 81 (66–141) | 153 (125–194) | 71 (64–88) | < 0.001 |
Indexed LV end-systolic volume (mL/m2) | 30 (20–56) | 75 (43–90) | 24 (19–31) | < 0.001 |
LV EF (%) | 63 (57–71) | 57 (45–61) | 66 (58–75) | < 0.001 |
LV EF <50% | 15 (15.2%) | 12 (37.5%) | 3 (4.5%) | < 0.001 |
LV mass index (g/m2) | 92 (76–118) | 110 (91–134) | 86 (71–104) | 0.001 |
Regurgitant volume (mL) | 65 (45–96) | |||
Regurgitant fraction (%) | 50 (40–63) | |||
Aortic valve area (cm2) | 0.7 (0.6–0.8) | |||
Peak gradient (mmHg) | 69 (58–93) | |||
Presence of LGE | 38 (38.4%) | 10 (31.3%) | 28 (41.8%) | 0.313 |
LGE mass (g) | 3.8 (2.0–8.3) | 3.8 (2.7–5.8) | 3.4 (1.5–9.6) | 0.586 |
LGE fraction (%) | 2.0 (1.0–3.8) | 1.9 (1.1–2.2) | 2.5 (1.0–5.2) | 0.463 |
Septal ECV w/o LGE (%) | 28.4 (26.0–32.6) | 30.2 (27.3–34.5) | 27.9 (24.7–30.6) | 0.015 |
Global ECV w/o LGE (%) | 27.3 (24.9–29.6) | 28.2 (26.5–31.6) | 26.8 (24.5–28.8) | 0.019 |
Septal ECV with LGE (%) | 28.4 (26.1–33.4) | 31.9 (27.7–35.3) | 27.9 (25.5–31.4) | 0.010 |
Global ECV with LGE (%) | 27.9 (25.0–30.7) | 28.4 (27.0–31.9) | 27.1 (24.7–29.3) | 0.048 |
Indexed cellular mass (g/m2) | 65.8 (55.0–82.8) | 79.8 (65.8–92.5) | 61.0 (51.9–74.4) | 0.001 |
iECV (mL/m2) | 24.2 (18.8–33.6) | 30.0 (22.8–39.6) | 22.0 (17.2–30.5) | 0.001 |
Values are expressed as n (%) or median (p25–p75). Bold P values indicate statistical significance.
CMR, cardiovascular magnetic resonance; ECV, extracellular volume fraction; EF, ejection fraction; iECV, indexed extracellular volume; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle; w/o, without.