Table 5.

Univariable and multivariable predictors for decrease in iECV^a after aortic valve replacement in aortic stenosis

	Univariable analysis		Multivariable analysis
	Beta (95% CI)	P value	Beta (95% CI)	P value
Clinical parameters
Age (years)	−0.304 (−0.374 to −0.04)	0.016		NS
Male sex	0.354 (1.311 to 6.93)	0.005		NS
Baseline functional class (NYHA)	−0.329 (−4.533 to −0.674)	0.009		NS
Echocardiographic parameters
Echo EF (%)	−0.403 (−0.599 to −0.156)	0.001	−0.370 (−0.623 to −0.012)	0.043
Echo ESV (mL)	0.282 (0.010 to 0.197)	0.030		NS
Echo LV systolic diameter (mm)	0.349 (0.138 to 0.765)	0.005		NS
Baseline CMR parameters
CMR EF (%)	−0.415 (−0.320 to −0.089)	0.001		NS
Indexed LV EDV (mL/m2)	0.457 (0.056 to 0.169)	<0.001		NS
Indexed LV ESV (mL/m2)	0.472 (0.070 to 0.200)	< 0.001		NS
Indexed mass (g/m2)	0.537 (0.070 to 0.165)	< 0.001		NS
LGE mass (g)	−0.509 (−0.515 to −0.080)	0.009		NS
LGE fraction (%)	−0.558 (−1.367 to −0.299)	0.004		NS
Septal ECV w/o LGE (%)	0.255 (0.002 to 0.599)	0.049		NS
Global ECV w/o LGE (%)	0.437 (0.305 to 1.010)	< 0.001		NS
Global ECV with LGE (%)	0.429 (0.280 to 0.947)	< 0.001		NS
iECV (mL/m2)	0.612 (0.274 to 0.548)	< 0.001	0.528 (0.136 to 0.702)	0.006
Laboratorial parameter
Baseline BNP (pg/mL)	0.321 (0.002 to 0.014)	0.011		NS
Surgical parameter
Prosthesis size (mm)	0.305 (0.180 to 1.827)	0.018		NS

Bold P values indicate statistical significance.

BNP, B-type natriuretic peptide; CI, confidence interval; CMR, cardiovascular magnetic resonance; ECV, extracellular volume fraction; EDV, end-diastolic volume; ESV, end-systolic volume; EF, ejection fraction; iECV, indexed extracellular volume; LGE, late gadolinium enhancement; LV, left ventricle; NYHA, New York Heart Association; NS, non-significant; SV, stroke volume; w/o, without.

Preoperative iECV minus postoperative iECV.