Table 1.
Categorical variables by phosphate quartile group (unique patients).
| Variable | Overall | Highest quartile | Third quartile | Second quartile | Lowest quartile | P-value |
|---|---|---|---|---|---|---|
| Age, years* | 60 (50, 71) | 64 (53, 74) | 60 (49, 73) | 59 (49, 70.5) | 58 (48, 68) | <0.001 |
| Gender, female | 950 (51) | 219 (54) | 233 (52) | 238 (52) | 260 (48) | 0.39 |
| Race, Black | 889 (48) | 190 (46) | 226 (50) | 211 (46) | 262 (49) | 0.34 |
| Other | 92 (5) | 14 (4) | 18 (4) | 25 (5) | 34 (6) | |
| White | 874 (47) | 204 (50) | 207 (46) | 220 (48) | 243 (45) | |
| AIDS | 61 (3) | 11 (3) | 18 (4) | 14 (3) | 18 (3) | 0.75 |
| Malignancy† | 210 (11) | 47 (11) | 56 (12) | 50 (11) | 57 (11) | 0.83 |
| CHF | 388 (21) | 127 (31) | 85 (19) | 92 (20) | 84 (16) | <.001 |
| COPD | 629 (34) | 149 (36) | 145 (32) | 184 (40) | 151 (28) | <.001 |
| CVD | 180 (10) | 53 (13) | 37 (8) | 44 (10) | 46 (9) | 0.08 |
| Diabetes | 637 (34) | 144 (35) | 165 (37) | 158 (35) | 170 (32) | 0.40 |
| Dementia | 104 (6) | 31 (8) | 35 (8) | 17 (4) | 21 (4) | 0.01 |
| Liver disease | 207 (11) | 47 (11) | 45 (10) | 53 (12) | 62 (12) | 0.84 |
| Myocardial infarct | 152 (8) | 54 (13) | 33 (7) | 28 (6) | 37 (7) | <.001 |
| Mechanical vent | 116 (6) | 50 (12) | 28 (6) | 21 (5) | 17 (3) | <.001 |
| Metastatic cancer‡ | 78 (4) | 16 (4) | 22 (5) | 19 (4) | 21 (4) | 0.87 |
| Vasopressors | 532 (29) | 204 (50) | 105 (23) | 111 (24) | 112 (21) | <.001 |
| Calcium, mg/dL*^ | 9.1 (8.6, 9.5) | 9 (8.4, 9.5) | 9.1 (8.6, 9.6) | 9 (8.6, 9.5) | 9.1 (8.6, 9.5) | 0.07 |
| Creatinine, mg/dL *^ | 1.09 (0.78, 1.65) | 1.73 (1.12, 2.73) | 1.11 (0.77, 1.76) | 0.94 (8.6, 9.5) | 0.99 (0.74, 1.33) | <.001 |
| Lactate, mmol/L*^ | 2.0 (1.4, 3.1) | 2.3 (1.5, 3.9) | 1.7 (1.2, 2.8) | 1.9 (1.2, 3.0) | 2.0 (1.5, 3.0) | <.001 |
| SOFA Total*^ | 2 (0, 5) | 5 (3, 8) | 5 (3, 8) | 2 (0, 4) | 1 (0, 3) | <.001 |
†
Any malignancy except malignancy skin neoplasm;
‡
metastatic solid tumor; data is reported as count (percentage) and analyzed using chi-square test, unless specified by
*
median (1st quartile, 3rd quartile) and Wilcoxon rank-sum test;
^
first available measure at first encounter.
AIDS, acquired immunodeficiency syndrome; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CVD, cerebrovascular disease; mg/dL, milligram per deciliter; SOFA, Sequential Organ Failure Assessment,