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. 2023 Jun 21;9(25):eadg7865. doi: 10.1126/sciadv.adg7865

Fig. 3. SARS-CoV-2 spike neutralization assays.

Fig. 3.

Neutralization assay against SARS-CoV-2 pseudotyped lentivirus (A) and Victoria live virus (B) for four CogMol-generated compounds with DMSO as a control. (C) The most effective compound, GEN727, was selected for a pseudoviral neutralization assay against Victoria, Alpha, Beta, Gamma, Delta, and Omicron variants of concern (VOCs), as well as (D) the live virus neutralization assay. Error bars show the standard error of each measurement over two trials.