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. 2023 May 17;618(7966):774–781. doi: 10.1038/s41586-023-06079-4

Extended Data Fig. 7. Empirical PGS accuracy decreases with genetic distance in UKBB averaged across 84 traits.

Extended Data Fig. 7

(a) Empirical PGS accuracy decreases across subcontinental GIA clusters. (b) Empirical PGS accuracy decreases across bins of GD. The x-axis is the average GD for all individuals within each GIA cluster or GD bin; the y-axis is the accuracy for each GIA cluster or GD bin. The dot and error bar show mean and ±1.96 standard error of the mean across 84 traits.