Extended Data Fig. 1. The individual level accuracy is highly correlated with population level accuracy.

All UKBB testing individuals are divided into 100 bins based on their GD. The x-axis is the average individual-level PGS accuracy for the individuals within the bin and the y-axis is (a) the squared correlation between simulated genetic liability and PGS estimates for the individuals within the bin (b) the squared correlation between simulated phenotype and PGS estimates. The dot and error bars represent the mean and ±1.96 s.e.m from 100 simulations. Both p-values were derived from two-sided Pearson correlation tests without adjustment for multiple hypothesis testing. Any p-value below ${10}^{-10}$ is annotated as $p<{10}^{-10}$.