Table 2.
Assessment of anti-HSV-1F activity of HL1 and HL2
| Test compound | CC50a | EC50b | Selectivity indexc |
|---|---|---|---|
| HL2 | 362.6 ± 2.5 | 37.2 ± 2.8 | 9.7 |
| HL1 | 270.4 ± 3.2 | 63.4 ± 3.0 | 4.3 |
| Acyclovir | 128.8 ± 3.4 | 2.8 ± 0.1 | 49.3 |
aCC50 of HL1 and HL2 in Vero cells at µg/ml
b50% reduction of virus mediated toxicity by HL1 and HL2 (µg/ml)
cSelectivity Index (SI) = CC50 × (1/EC50)