FIGURE 6.

BW and activity in sEH inhibitor treatment experiment. (A). BW before exposure (week 0). There was no difference among the three groups (p > 0.05, one-way ANOVA). (B). Weight gain over the 16 weeks. FA-TPPU group had significantly greater weight gain than the FA-H₂O and SHS-TPPU groups (two-way repeated ANOVA). (C). Activity level (expressed as Δ% of the mean values from the FA-H₂O group) after 4, 8, and 12 weeks of exposure. SHS-TPPU mice had significantly higher activity levels than those of FA-TPPU mice (two-way repeated ANOVA followed by Fisher’s LSD tests). (D). Activity levels after 4 weeks of cessation from SHS exposure and TPPU treatment. The SHS-TPPU mice still had higher activity level during dark cycles (t-test). Significant main effects from ANOVA are indicated with “+”. *p < 0.05, FA-TPPU vs. SHS-TPPU. Numbers in parentheses indicate sample sizes.