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. 2023 Mar 25;27(3):102759. doi: 10.1016/j.bjid.2023.102759

Table 2.

In vitro susceptibility of Enterobacterales collected in six Latin American countriesa divided into two 3-year time periods 2015‒2017 and 2018‒2020.

Collection years (n) Compound Range MIC50 MIC90 CLSI Interpretationb
(µg/mL) %S %I %R
2015‒2017 (7736) Amikacin ≤0.25 – >32 2 8 96.5 1.6 1.8
Aztreonam ≤0.015 – >128 0.12 128 69.2 1.9 28.9
Cefepime ≤0.12 – >16 ≤0.12 >16 71.0 5.5 23.4
Ceftazidime ≤0.015 – >128 0.25 64 70.9 3.3 25.9
Ceftazidime-avibactam ≤0.015 – >128 0.12 0.5 99.3 NA 0.7
Colistin ≤0.06 – >8 0.25 >8 NA 83.0 17.0
Imipenem ≤0.03 – >8 0.25 2 84.6 7.5 7.8
Levofloxacin ≤0.004 – >8 0.25 >8 61.1 5.5 33.4
Meropenem ≤0.004 – >8 0.03 0.12 94.6 0.8 4.6
Piperacillin Tazobactam ≤0.25 – >128 4 128 77.9 4.3 17.8
2018‒2020 (7479) Amikacin ≤0.25 – >64 2 8 94.8 2.3 2.9
Aztreonam ≤0.015 – >128 0.12 >64 63.6 2.7 33.7
Cefepime ≤0.12 – >32 ≤0.12 >32 64.5 7.7 27.7
Ceftazidime ≤0.015 – >128 0.5 >64 64.5 3.7 31.8
Ceftazidime-avibactam ≤0.015 – >128 0.12 1 97.2 NA 2.8
Colistin ≤0.06 – >8 0.5 >8 NA 80.2 19.8
Imipenem ≤0.06 – >8 0.25 4 80.1 6.6 13.3
Levofloxacin ≤0.25 – >8 0.5 >8 58.8 6.6 34.5
Meropenem ≤0.06 – >16 ≤0.06 1 90.4 1.0 8.6
Piperacillin Tazobactam ≤0.12 – >64 2 >64 73.8 5.5 20.7
a

Countries included Argentina, Brazil, Chile, Colombia, Mexico, and Venezuela.

b

S, susceptible; I, intermediate; R, resistant.