Table 3.
Matrix effect and extraction recovery for the determination of cinacalcet.
| Nominal concentration (ng/mL) | Matrix effect |
Extraction recovery |
||
|---|---|---|---|---|
| IS-normalized matrix effect (%) | CV (%) | Recovery rate (%) | CV (%) | |
| 0.3 | 99.99 ± 5.09 | 5.09 | 101.04 ± 4.48 | 4.43 |
| 5 | 101.32 ± 2.33 | 2.30 | 101.50 ± 5.49 | 5.41 |
| 20 | 99.17 ± 1.91 | 1.93 | 102.88 ± 4.78 | 4.65 |
| 35 | 102.22 ± 1.02 | 0.99 | 95.67 ± 5.44 | 5.69 |