Table 3.
Baseline clinical characteristics of the study subjects.
| Characteristics | All patients | Healthy controls | Septic shock | P value |
|---|---|---|---|---|
| Demographics and underlying conditions | ||||
| Number of patients | 58 | 28 | 30 | — |
| Males, number (%) | 39(67.2%) | 16(57.1%) | 27(76.6%) | — |
| Age (years) | 63.5(49.25-72.75) | 70.5(63-80.5) | 58.5(44.5-67) | 0.0199 |
| Hypertension, number (%) | 19(32.7%) | 8(28.5%) | 11(36.6%) | — |
| Type 2 Diabetes mellitus, number (%) | 11(18.9%) | 4(6.8%) | 7(23.3%) | — |
| Laboratory value, mean ± SEM | ||||
| PCT (μg/L) | — | 0.2 ± 0.1 | 37.6 ± 4.9 | <0.0001 |
| CRP (mg/L) | — | 8.1 ± 3.7 | 93.5 ± 5.1 | <0.0001 |
| Lactate (mmol/L) | — | 0.6 ± 0.1 | 5.2 ± 1.2 | <0.0001 |
| Site of infection, number (%) | ||||
| Lung | — | — | 14(46.6%) | — |
| Abdomen | — | — | 6(20.0%) | — |
| Urinary tract | — | — | 4(13.3%) | — |
| Other | — | — | 6(20.0%) | — |
| Origin of the infection, number (%) | ||||
| Viral originated | — | — | 7(23.3%) | — |
| Bacterial originated | — | — | 18(60.0%) | — |
| Other | — | — | 5(16.7%) | — |
| Length of stay | ||||
| In the ICU (days) | 6(0-6) | 0 | 15.5(4.5-24.25) | <0.0001 |
| In the hospital (days) | 15(10.75-25.25) | 15(10.75-25.25) | 26.5(14.5-39.25) | 0.0021 |
| APACHE II score | 19(13-24) | 0 | 19(15-25) | <0.0001 |
| SOFA score | 6(4-10) | 0 | 6.5(4-11) | <0.0001 |
APACHE II, acute physiology and chronic health evaluation score; SOFA, sequential organ failure assessment score. Data is presented as median (interquartile range); P-value is analyzed by chi-square (gender and site of infection), Kruskal-Wallis test (age) or Mann-Whitney U test (APACHE II score, SOFA score).