RT-PCR analysis of Alox15
(A) and Alox5
(B) expression in immunoglobulin E-activated (αIgE) and not-activated (NA) laboratory of allergic diseases 2 (LAD-2) cells, preincubated with 20 μM docosahexaenoic acid (DHA), 30 min, 1.5 and 24 h after activation. (*p<0.05, ***p<0.001). (C) Representative histogram of 15-lipoxygenase protein expression in cord blood-derived mast cells (CBMCs) preincubated with 20 μM docosahexaenoic acid (DHA) 30 min after IgE-mediated activation. RT-PCR analysis of Alox15
(D) and Alox5
(E) expression in IgE-activated and not-activated foreskin-derived mast cells (FSMCs), preincubated with 20 μM docosahexaenoic acid (DHA), 1h after activation. Data are expressed as mean ± SEM of three independent experiments.