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. 2023 Jun 22;13(28):18991–19001. doi: 10.1039/d3ra02490c

MIC of compounds 24b and 24c against NDM, VIM and IMP expressing bacteria.

MBL-producing bacteria Minimum inhibitory concentration (mg L−1)a
Meropenem 24b Meropenem 24c
E. coli NDM-4 0.06 8 0.25 8
E. coli IMP-1 0.03 8 0.5 8
E. coli IMP-8 0.125 8 0.25 8
Enterobacter cloacae NDM-1 0.25 8 0.25 8
E. cloacae VIM-1 0.5 8 0.25 8
a

All assays were conducted in triplicate p < 0.001.